While I am not a nutritionist, many clients ask me about healthy nutrition. After fourteen years of experience with thousands of clients, some of whom are nutritionists, and much research for  personal and professional interests, here is a list of ingredients to consider consuming daily for sustaining nourishment. Oh – bread is not on the list!

(This list is intended  for educational purposes and solely for your consideration. Each body has unique nourishment needs. Please seek qualified health professionals for guidance.)

 

Click each item’s “+” sign to view a brief explanation, with information like health benefits, product forms, daily recommended quantities, and sources for purchase.

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Our bodies, like our lives, are unique, dynamic and subject to change with the seasons and varying degrees of stress and activity. Hence our nutrient needs fluctuate and should be customized to our own body. Our diet should be nutrient-dense, not calorie-rich, and include proper preparation and cooking methods that enhance nutrient availability and/or reduce naturally-occurring anti-nutrients. It should include living, raw, leafy, colorful, alkalizing, antioxidant and enzyme rich, organic foods. It must include healthy fats, as the human body is designed to metabolize fats, not high sugar content, and needs healthy fats to digest proteins and other nutrients, produce hormones, and support many other functions. (Cholesterol too… the brain is comprised of fat that is high in cholesterol.) Below are healthful considerations to augment one’s diet.
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See our article Why the Quality and Quantity of Your Water is Vital to Your Health[/toggle]
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See our article Mineralize or Die![/toggle]
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See our article: Alkalizing Diets Slow the Progression of Cancer[/toggle]
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As a reminder, vitamins cannot function in the body without minerals, or be well absorbed without healthy fats. Choose a good whole-food multi-vitamin (non synthetic) that provides a broad spectrum of vitamins beyond just the ABCs. Look for vitamins E, K, K2, etc. as well. Remember that a good multivitamin cannot make up for a poor diet.

Colorful and leafy produce can help provide a broad-spectrum of vitamins. But since we may not be able to eat the volume and variety of produce necessary to yield an adequate full spectrum of vitamins, supplementation can help.

Have you ever wondered why the ingredients label of a multi-vitamin bottle lists some vitamins having say, 1333% of the Recommended Daily Allowance? Or why such high amounts wouldn’t lead to toxicity? It’s because our bodies can only assimilate a fraction of the amount. However, the body assimilates natural forms and food-based vitamins more readily than synthetic forms.

To enhance the absorption of a multi-mineral supplement, consider consuming them with healthy fats, as some vitamins are fat-soluble while others are water-soluble. Also consider taking your supplement at mealtime for a synergistic effect. (I use New Chapter’s 40+ Every Woman Multivitamin, consuming 3 tablets daily.)
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Because some vitamins and minerals are more important than others, or can support specific needs, consider supplementing with a few individual vitamins and minerals, including those below.
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[toggle title_open=”… Vitamin D3″ title_closed=”… Vitamin D3″ hide=”yes” border=”yes” style=”default” excerpt_length=”0″ read_more_text=”Read More” read_less_text=”Read Less” include_excerpt_html=”no”]

The bad news: Many women diagnosed with breast cancer have been found to be deficient in vitamin D. Could their diagnosis have been prevented? The good news: optimizing blood levels of Vitamin D may significantly reduce the risk of more than a dozen types of cancer, including breast, pancreatic, colorectal, ovarian, and prostate. When it comes to breast cancer prevention, vitamin D may be the most important vitamin of them all.

 

Vitamin D Inhibits Cancer

According to the National Center for Biotechnology Information, “Calcitriol (1,25-dihydroxyvitamin D3), the hormonally active metabolite of vitamin D, inhibits the growth of many malignant cells including breast cancer cells” by inhibiting estrogen synthesis. ”Calcitriol and its anti-inflammatory actions will play an important role in the prevention and/or treatment of breast cancer.” [i]

 

Vitamin D US RDA is Too Low

Many vitamin D health experts recognize that the US RDA of vitamin D is inadequate for optimal health. And because each of us assimilates vitamin D uniquely, it is better to monitor the result of dosage rather than the dosage itself. That way you can adjust the dosage to achieve the desired effect.

The most accurate way to measure how much vitamin D is in your body is the 25-hydroxy vitamin D blood test. A level of 50 nanograms/milliliter to 70 ng/mL is considered optimal for healthy people. (70 – 100 ng/mL is recommended when treating cancer and heart disease.) This is in stark contrast to the medical standard suggesting that 20 ng/mL is adequate.

The optimal range offers greater protection from issues including not only osteomalacia (softening of the bones), osteopenia (reduced bone mass), and osteoporosis (brittle, fragile bones), but also thyroid conditions, kidney disease, heart disease, autoimmune disorders, cancers and more.[ii]

There is no risk of toxicity until achieving levels above 200 ng/ml. So 200 ng/ml is the higher threshold for toxicity, and 40 ng/ml is the lower threshold for therapeutic benefit. Ask your health provider or order your 25-hydroxy vitamin D blood test on-line (perhaps through the Vitamin D Council.)

 

Forms of Vitamin D

While vitamin D2 is available through plant-based sources, it is D3 that we really need. D3 is far more beneficial to our health than D2 and only available through animal-based sources like fatty fish, animal livers, egg yolk and raw (unpasteurized) milk. (Cod liver oil is a potent source of D3.) When exposed to sunshine, our skin also synthesizes vitamin D3, which is water soluble, while oral vitamin D3 supplements are fat soluble.

In Colorado we live well above the equator, where there is insufficient ultraviolet-B radiation for vitamin D synthesis from November to early March. Because sunlight won’t be sufficient at certain times of the year or in certain places, and because the body’s ability to manufacture vitamin D declines with age, nutritional supplementation is essential for sustaining optimal blood levels.

 

Medical Conditions that Increase the Need for Vitamin D

Vitamin D must pass through the liver and the kidneys in order to become available for active use by the body. Hence, diseases of those organs can affect the formation of active vitamin D, including:

Alcoholism
Intestinal diseases such as Crohn’s, celiac, cystic fibrosis
Kidney disease leading to failure
Liver disease
Overactivity of the parathyroid glands
Pancreatic disease
Surgical removal of the stomach
Surgical removal of the end of the small bowel (terminal ileum)

Supplementing with active forms may be necessary. However, these forms are not mere supplements, so doctors prescribe them as part of a treatment regimen.

 

Medications that Interfere with the Absorption of Vitamin D

Antacids and acid blcokers: Tagamet, Pepcid, Axid, Zantac
Barbiturates
Carbamazepine
Cholestyramine
Colestipol
Fosphenytoin
Heparin
Highly Active Antiretroviral Therapy, (for AIDS)
Isoniazid
Mineral oil or products containing mineral oil
Orlistat
Phenobarbital
Phenytoin
Rifampin
St. John’s Wort

 

How to Take Oral D3

When you increase your intake of vitamin D3, be sure to increase your intake of vitamin K2. And because vitamin D3 is a fat-soluble vitamin, it is best taken with healthy fats like organic: avocado, coconut and nut; and organic, pasture/grass-fed: butter, clarified butter (ghee), egg yolk, and meat. Vitamin D3 also needs sufficient amounts of magnesium, zinc and other trace minerals to work properly, so be sure to stay adequately mineralized each day. For more information on vitamin K2, healthy fats and minerals, please see their separate sections in this document.

While a dosage of only 5,000 IUs of vitamin D3 a day may enable you to reach and maintain a blood level of at least 40 ng/ml, I typically consume 5,000 – 20,000 IUs of Vitamin D3 daily via Thorne Vitamin D/K2 sublingual drops, available at Amazon.com and many health food stores. (I used to use: Carlson D3 drops and Biotics Emulsified D3 drops, but found them less absorbable for me and they do not include Vitamin K2.) It’s important to find the formula and dosage best for your body. I typically consume vitamins D and K with a meal that includes butter, Green Pastures Fermented Cod Liver Oil, or New Chapter WholeOmega since these are fat-soluble vitamins.

 

[i] Krishnan AV, Swami S, Feldman D. Vitamin D and breast cancer: inhibition of estrogen synthesis and signaling. J Steroid Biochem Mol Biol. 2010 Jul;121(1-2):343-8. doi: 10.1016/j.jsbmb.2010.02.009. Epub 2010 Feb 13. (Pubmed 20156557)

[ii] Mayo Clinic
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[toggle title_open=”… Vitamin K: Fight Plaque, Build Bone” title_closed=”… Vitamin K: Fight Plaque, Build Bone” hide=”yes” border=”yes” style=”default” excerpt_length=”0″ read_more_text=”Read More” read_less_text=”Read Less” include_excerpt_html=”no”]

Vitamin K refers to the group of fat soluble vitamins, essential for blood coagulation and for binding calcium to the bone. Without adequate vitamin K, vitamin D cannot improve bone density, our blood does not coagulate (leading to uncontrolled bleeding) and our arteries and other soft tissues become calcified. Egads. Let’s take a serious look at this under-estimated powerhouse of a vitamin.

 

Forms of Vitamin K: K1, K2, K3, K4 and K5

There are five known forms of vitamin K: K1 and K2 are natural, and K3, K4 and K5 are synthetic. The synthetic forms are used primarily in industry. K vitamins are similar in structure: they share a ring structure with varying lengths and “side chains” of molecular units. The number of side chains influences which forms of vitamin K are transported to various tissues.

Vitamin K1, also known as phylloquinone, phytomenadione, and phytonadione, occurs in plants, especially green leafy plants since it is involved in photosynthesis. This plant-derived vitamin K is the form most involved in blood clotting in our bodies.

Healthy bodies convert a large portion of K1 to K2. Vitamin K2, also known as menaquinone, has several subtypes, each characterized by its composition and number of side chains. Menaquinones are abbreviated MK-n: M stands for menaquinone, K stands for vitamin K, and n stands for the number of side chains.

The most common type of K2 in animal tissues and products is MK-4. Typically synthesized from K1 in certain animal tissues like arterial walls, pancreas, and testes, MK-4 delivers enzymatic functions distinct from those of K1. Bacteria in the large intestine can also convert K1 into K2, delivering the longer-chain menaquinones like MK-7 – MK-9, which are crucial for calcium plaque removal from our arteries.

 

Health Benefits of Vitamin K

While K1 is used by the liver to activate blood clotting proteins that stop bleeding, K2 is essential in the removal of excess minerals from soft tissue and vascular walls, i.e. the kidneys and arteries, and in the delivery and composition of calcium and minerals in the bone and teeth.

 

K1: Blood Coagulation

Without adequate K1, we can experience anemia, bruising, and uncontrolled bleeding.

 

K2: Teeth and Bone Composition

K2 activates proteins that remove calcium from the lining of blood vessels and deposit it to the bone. Osteocalcin is a protein that organizes the composition of calcium and phosphorus in bone and teeth. Osteocalcin is dependent upon K2 to perform this function. Without adequate K2, bones become fragile and fracture risk increases. Vitamin K2 as MK-4 and MK-7 increase levels of activated osteocalcin and significantly reduces the incidence of bone fractures.

 

K2: Arterial Calcification

Patients suffering from osteoporosis can have extensive calcium plaque in the arteries, impairing blood flow. “This simultaneous excess of calcium in one part of the body (arteries), and lack in another (bones) – which may occur even in spite of calcium supplementation – is known as the Calcium Paradox.”[i]

The underlying cause is K2 deficiency. Vascular calcification might not only be prevented, but even reversed by increasing the daily intake of K2. K2 activates the protein that binds with arterial calcification. The long-chain subtypes of K2 (MK-7 through MK-9) are the most important for preventing excessive calcium accumulation in the arteries.[ii]

 

Coumadin and K2 Supplementation

Nearly 10% of Americans use the blood thinner Warfarin, also known as Coumadin.  This treatment disrupts vitamin K metabolism and reduces active osteocalcin levels and bone mineral density/composition, so patients can experience significantly increased osteopenia, bone fractures and soft-tissue and vascular calcification.

Since vitamin K can reverse the blood-thinning effect of Warfarin (Coumadin), patients are typically advised to avoid diets rich in K vitamins. However, the latest research proposes combining K2 with anticoagulation treatment to stabilize blood coagulation while reducing Warfarin-induced arterial calcification. Alternatively, newer anticoagulants like Dabigatran and Rivaroxaban do not interact with vitamin K, so K2 supplementation may reduce arterial calcification without interfering with anticoagulation treatment.

 

Statins and K2 Supplementation

Nearly 25% of US adults over age 40 use a statin drug. “Not only do all of these people need to take a ubiquinol or coenzyme Q10, which is also depleted by the drug, it’s quite likely they also need vitamin K2 to avoid cardiovascular harm.”[iii]

 

Sources of Vitamin K

Vitamin K2 is preferred by the tissues outside the liver, including bone, cartilage and blood vessels. “tissues that accumulate high amounts of MK-4 have a remarkable capacity to convert up to 90% of the available K1 into MK-4.”[iv],[v]

While the MK-4 subtype appears most predominant in animal tissues, other MK numbers found there are derived from bacterial origin.

Except for MK-4, all subtypes of K2 are produced by bacteria, most notably in the large intestine. Large intestine bacteria convert K1 into vitamin K2 subtypes, particularly MK-7 through MK-11. The body’s utilization of MK-7 over MK-4, if any, is unclear and needs further investigation, as does the body’s utilization of the other long-chain subtypes, whose functions are less understood.

The richest dietary sources of long-chain menaquinones are animal livers and bacterial fermented foods like ripe (Gouda, Brie, Edam and Cheddar) cheeses and vegetables fermented with K2-producing bacteria in Western diets and natto (fermented soybeans and Bacillus subtilis) in Japan. Natto is an exceptionally rich source of MK-7. MK-4 is often found in relatively small quantities in grass-fed (not feed lot) meat (including fats, livers and organs), butter and eggs.

 

How Much Vitamin K Do I Need?

The US Daily Adequate Intake levels of vitamin K are:

25 year-old male:             120 micrograms (μg)
adult women:                    90 μg
infants:                                 10–20 μg
children/adolescents:   15–100 μg

However, the Ministry of Health in Japan has approved 45 mg of MK-4 daily for the prevention and treatment of osteoporosis.[vi] Hence, “adequate intake” does not necessarily correspond to “optimal intake.”

Also, the half-life of MK-4 is much shorter than that of MK-7, so while a single serving of MK-7 daily may be adequate, multiple servings, i.e. three, of MK-4 spread throughout the day may be warranted.

Dr. Dennis Goodman, cardiologist and chairman of the Department of Integrative Medicine at New York University, and author of the book, Vitamin K2: The Missing Nutrient for Heart and Bone Health, recommends taking 180 μg per day, in the form of MK-7 (the equivalent of about one teaspoon of natto).

 

You May Need More Vitamin K

Individuals at risk for K2 deficiency are those whose intestines have been seriously damaged or compromised, resulting in malabsorption, and those subjected to broad spectrum antibiotic use, which can significantly reduce K2 production. Newborn infants are at an increased risk of deficiency and the elderly typically experience reduced K2 production.

Other populations include those who suffer from kidney disease, liver damage or disease (e.g., alcoholics), cystic fibrosis, or inflammatory bowel diseases, or have recently had abdominal surgeries. Secondary vitamin K deficiency can occur in bulimics, those on stringent diets, and those taking anticoagulants. Other drugs associated with vitamin K deficiency include salicylates (i.e. aspirin), barbiturates, and cefamandole (i.e. Mandol, a broad-spectrum antibiotic).

Symptoms of K1 deficiency include anemia, bruising, and bleeding of the gums or nose, and heavy menstrual bleeding in women. Osteoporosis, severe aortic calcification and coronary heart disease are strongly associated with lower levels of K2.

 

Toxicity of Vitamin K

While there are no known toxic levels for its natural forms, K1 and K2, the “FDA has banned K3 from over-the-counter sales because large doses have been shown to cause allergic reactions, hemolytic anemia, and cytotoxicity in liver cells.” K3 (menadione) is  used in some pet foods.

 

[i] Wikipedia

[ii] Gast et al. A High Menaquinone Reduces the Incidence of Coronary Heart Disease in Women. Nutrition, Metabolism and Cardiovascular Diseases. Sep 2009; Vol.19 No.7, pp.504–510. PMID 19179058

[iii] Mercola: Vtamin K2 Health Benefits

[iv] Davidson, RT; Foley AL; Engelke JA; Suttie JW. Conversion of Dietary Phylloquinone to Tissue Menaquinone-4 in Rats is Not Dependent on Gut Bacteria. Journal of Nutrition. 1998; 128 (2): 220–223. PMID 9446847

[v] Ronden, JE; Drittij-Reijnders M-J; Vermeer C; Thijssen HHW (1998). Intestina Flora is not an Intermediate in the Phylloquinone-Menaquinone-4 Conversion in the Rat. Biochimica et Biophysica Acta (BBA) – General Subjects 1379 (1): 69–75. doi:10.1016/S0304-4165(97)00089-5. PMID 9468334

[vi] Iwamoto, I; Kosha S; Noguchi S-i. A Longitudinal Study of the Effect of Vitamin K2 on Bone Mineral Density in Postmenopausal Women – a Comparative Study with Vitamin D3 and Estrogen-Progestin Therapy. Maturitas, 1999; 31 (2): 161–164. doi:10.1016/S0378-5122(98)00114-5. PMID 10227010
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The following items are under development.

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Synthetic iodized salt.[/toggle]
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Our mission at The Thermogram Center, Inc. is preventive education. Environmental causes of human cancer are manageable. However, the public remains unaware of the many common environmental carcinogens and the actions necessary to mitigate their risk. We hope to be a reliable source of information to help you protect you and your family from the hazardous chemicals in the air, water, food, and products threatening your well being.

by Tirza Derflinger
Founder, Author, Lead Educator, Speaker, CTT, MBA
Better Breast Health – For Life!™
Be the Cure. Seek Prevention.
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